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Nursing Field Notes / Mental Health · Psychiatric Care Course

Schizophrenia 🧠

Signs & Symptoms — Part 1 of a 4-page Schizophrenia series

NG-049 Mental Health Series 1 of 4 · foundation page

Schizophrenia is a chronic thought disorder — an abnormal, scattered pattern of thinking and perceiving lasting 6 months or more, disrupting relationships, school, and work. This page defines every term the rest of the series reuses: positive, negative & cognitive symptoms, hallucinations, delusions, and disorganized speech. Communication techniques live on NG-128; drug therapy lives on NG-165 & NG-235.

📄 Simple Nursing original — opens in Drive →

➕ Positive = ADDEDSomething normal brains don't have: hallucinations, delusions, disorganized speech/behavior.
➖ Negative = TAKEN AWAYSomething normal brains do have but this client has lost: flat affect, avolition, anhedonia.
🧩 Cognitive = MEMORY & FOCUSTrouble with attention, memory, executive function & insight.
🚨 Suicide risk = HIGHAlways priority-assess safety — highest yield fact on this whole page.
🧬

CAUSE

STEP 1 · WHAT STARTS IT

A dopamine imbalance in two different brain pathways explains why symptoms split into two opposite categories.

🧠 The dopamine hypothesis — two pathways, two opposite effects

Schizophrenia is linked to dysregulated dopamine signaling, but it isn't simply "too much" or "too little" everywhere — it depends on which pathway.

MESOLIMBIC excess dopamine ⬆️ → POSITIVE symptoms MESOCORTICAL deficit dopamine ⬇️ → NEGATIVE & COGNITIVE symptoms 💊 antipsychotics block D2 receptors here too — why they can worsen negative symptoms.
🧠 "MESO-LIMBIC = MORE limbic feelings" (positive) · "MESO-CORTICAL = COGNITIVE cortex" (negative/cognitive). Antipsychotics only fix the excess pathway — that's why negative & cognitive symptoms are the hardest to treat (see NG-235 for why).

🧬 Genetics & risk factors

  • Family history — a child is significantly more likely to develop schizophrenia when a parent has the condition; risk rises further with two affected parents.
  • Prenatal/perinatal factors — maternal malnutrition, viral infection, or obstetric complications are associated with higher risk.
  • Environmental stress + genetic vulnerability — the leading model is a "stress-diathesis": genetic predisposition plus a triggering stressor (adolescence/young-adulthood is the typical onset window).
🧠 Typical onset: late teens to early 30s — earlier and often more severe in men, slightly later in women.

📅 Diagnostic criteria — the 6-month rule

Standard criteria require ≥2 characteristic symptoms (delusions, hallucinations, disorganized speech, grossly disorganized/catatonic behavior, negative symptoms) for a significant portion of 1 month, with continuous signs of disturbance for ≥ 6 months, and a clear drop in functioning — work, relationships, self-care.

🧠 "6 & 1"6 months total disturbance, 1 month of active, full-blown symptoms in the middle of it.

⏳ The 3 phases — same illness, different intensity

1 · PRODROMAL Subtle early changes: social withdrawal, odd beliefs, declining function — before full psychosis appears. 2 · ACTIVE Full psychotic symptoms: hallucinations, delusions, disorganized speech/behavior — the acute episode. 3 · RESIDUAL Psychosis fades, but negative/cognitive symptoms and social withdrawal persist — functioning stays below baseline.
🧠 Relapse usually re-enters at the active phase, not from scratch — this is why medication adherence (NG-165) is the single biggest predictor of staying out of the active phase.
🔎

SYMPTOMS

STEP 2 · WHAT YOU'LL NOTICE

Three buckets. Positive = added on top of normal. Negative = subtracted from normal. Cognitive = the thinking machinery itself.

➕ Positive symptoms — psychotic symptoms, ADDED

"voices" 👂 audit. "they're watching & controlling me" 🎯 delusion ADDED to a normal brain

🗣️ Hallucinations — perceiving something that is not really there.

  • Auditory (most common) — hearing voices/sounds. Nursing action: offer structured, reality-based distraction such as headphones with music or a task that occupies attention.
  • Tactile — false sensation of being touched.
  • Also possible: visual, olfactory, gustatory (rarer — investigate for a medical/substance cause if prominent).

🎯 Delusions — a fixed false belief that persists despite evidence against it.

  • Persecutory (paranoid)"The hospital food is trying to poison me."
  • Grandeur"I have a meeting with the Queen today."
  • Reference"This song has a secret message just for me."
  • Control"I don't go online — that's how the FBI controls people."
🧠 "P-P-P"Positive = Psychotic = something Present that shouldn't be. See NG-128 for exactly what to say (and never say) when a client reports a hallucination or delusion.

➖ Negative symptoms — the 5 A's

  • Affect flat — expressionless, blank; mood looks "switched off"
  • Anhedonia — loss of ability to feel pleasure
  • Avolition — lack of motivation to start/finish goal-directed tasks
  • Alogia — poverty of speech, minimal spontaneous talking
  • Asocial — withdraws from social interaction, prefers isolation
🧠 Negative symptoms = a Negative photograph — the picture is missing pieces a normal brain has. These are the symptoms most easily missed because nothing dramatic is happening — the client is just quietly absent.

🧩 Cognitive symptoms — capacity to think

Impaired memory, attention, and executive function (planning, problem-solving, insight). Affects learning, understanding instructions, and — critically — insight into having an illness (see anosognosia on NG-165).

🧠 "C = Capacity." Cognitive symptoms are the ones that quietly sabotage medication adherence and discharge teaching — always check for understanding, don't just assume it.

📋 All three buckets, side by side

Positive (added)Negative (subtracted)Cognitive (thinking machinery)
HallucinationsFlat affectImpaired attention/concentration
DelusionsAnhedoniaImpaired memory
Disorganized speechAvolitionPoor executive function/planning
Grossly disorganized or catatonic behaviorAlogiaReduced insight (anosognosia)
Asociality
🧠 NCLEX trap: a question describing a client who is quiet, withdrawn, and unmotivated is testing negative symptoms, not "doing fine." Passive presentations get under-treated in real practice — don't let them get under-recognized on the exam either.
🗣️

DISORGANIZED SPEECH

STEP 2B · HOW THOUGHT DISORDER SOUNDS

A form of positive symptom on its own — the connective tissue between thoughts breaks down. Learn to recognize each pattern by name.

🧵 Loose associations — thoughts shift with no logical link

✅ ORGANIZED "How was your sleep?" "I slept about six hours, then woke up early." — each idea connects to the last ❌ LOOSE ASSOCIATIONS "The universe is like a raisin, but the moon is a home & I rode my bike."
🧠 "Loose = zig-zag." Each new sentence jumps to an unrelated idea — no thread connects them, unlike tangentiality where there's still a starting thread that trails off.

🆕 Neologisms & word salad

Neologisms — inventing new, made-up words with private meaning.

Word salad — real words strung together with no meaningful sentence structure: "Here is the chair, moon, orange, drank too much."

🧠 Neologism = a new logo for a word that never existed before.

🔔 Clang associations

Choosing words for how they sound (rhyme), not what they mean: "Let's go to the bay, hit the hay, what do you say — we can go today."

🧠 Clang = a bell (clang!) ringing on rhyme, not meaning.

🔁 Perseveration vs. echolalia

PerseverationEcholalia
Repeats the same word/phrase regardless of the question askedRepeats back what someone else just said
Nurse: "How do you feel?" → "Splendid." Nurse: "What's today's date?" → "Splendid."Nurse: "We will take your vitals." → Client: "Vitals."
🧠 Per-SEVER-ation SEVERs the connection to the actual question. Echolalia = a literal echo.

↩️ Tangentiality vs. concrete thinking

Tangentiality — replies veer off to unrelated topics and never return to the original question. Nurse: "How was your sleep?""When I was five my cat was killed, I love dogs."

Concrete thinking — takes abstract statements literally. "Grass is greener on the other side" is understood as literal grass, not the idiom.

🧠 Avoid idioms/metaphors in teaching — say exactly what you mean.
🩺

CARE PRIORITIES

STEP 3 · SAFETY FIRST

Suicide risk outranks everything else on this page. Everything after safety belongs on the other 3 pages in this series.

🚨 Suicide risk is HIGH — always assess first

1
Assess safety — suicidal ideation, plan, means, and command hallucinations (voices telling the client to harm self/others)
2
Provide a safe, low-stimulation environment — decrease noise, light, and crowding, which can worsen psychosis
3
Build trust — consistent staff, honesty, predictable routine (therapeutic milieu — detailed on NG-128)
4
Monitor continuously through every phase, not just during an acute admission
🧠 "S-S-S"Schizophrenia has a Scattered pattern of thinking and Suicide risk is high. Say it every time you see the diagnosis.

QUICK RECALL

SAY IT OUT LOUD
➕ PositiveHallucinations, delusions, disorganized speech/behavior
➖ NegativeFlat affect, anhedonia, avolition, alogia, asocial (5 A's)
🧩 CognitiveMemory, attention, executive function, insight
🚨 Suicide risk HIGHAssess every time — top priority in this whole disease
🎯 Cover & check — 4 rapid-fire questions
Q1: A client says "I don't hear any voices, but the ceiling cameras are watching me." Which symptom category and type?
Positive symptom — a persecutory (paranoid) delusion.
Q2: A client with schizophrenia sits alone, has a blank expressionless face, and rarely initiates conversation. Symptom category?
Negative symptoms — flat affect + asociality (part of the 5 A's).
Q3: Nurse asks "How was your sleep?" and the client answers "Absolutely splendid" to every question asked afterward. What is this called?
Perseveration — repeating the same response regardless of the question.
Q4: What is the single highest nursing priority whenever a client has a schizophrenia diagnosis?
Assess suicide risk / safety — it is HIGH across all phases of the illness.