🏠 Study Hub 🖼️ Infographics
NG-326

🩸 Ectopic & Molar Pregnancy

Early pregnancy bleeding sorted by where the pregnancy is. Shoulder pain means rupture; very high hCG means a mole.

🧬 Ectopic pregnancy

A uterus with the pregnancy implanted in one tube and blood from the rupture tracking up to irritate the diaphragm and refer pain to the shoulder, beside the same uterus filled with the grape-like tissue of a mole and an hCG gauge pinned at the top.
The referred shoulder pain stops being arbitrary once you can see the blood reaching the diaphragm. Swipe it sideways if it is cut off, or tap to open it full size.

A fertilised ovum implants outside the uterus — about 90% in a fallopian tube. The tube cannot stretch, so it eventually ruptures.

This is the leading cause of maternal death in the first trimester.

SignDetail
Classic triadMissed period + unilateral stabbing pain + spotting
Shoulder painRupture — blood in the abdomen irritates the diaphragm and refers to the shoulder
hCGRises more slowly than in a normal pregnancy
ShockTachycardia then hypotension; often more bleeding than is visible

Shoulder pain in early pregnancy is a ruptured ectopic until proven otherwise. It is a surgical emergency.

Risk factors: previous ectopic, PID or salpingitis, tubal surgery, endometriosis, IUD in place, smoking.

🩺 Care

  • Unruptured — may be treated with methotrexate. Teach: avoid folic acid supplements and alcohol, and no intercourse until hCG is undetectable
  • Ruptured — two large-bore IVs, type and crossmatch, oxygen, straight to theater
  • RhoGAM if Rh negative
  • Acknowledge the loss — this is a pregnancy loss as well as an emergency

🍇 Hydatidiform mole

Abnormal placental tissue grows instead of a fetus — grape-like vesicles filling the uterus.

SignDetail
hCGExtremely high — far above expected for dates
UterusLarger than dates
BleedingDark brown “prune juice”, may pass grape-like vesicles
Fetal heartAbsent; no fetus on ultrasound
OtherSevere nausea and vomiting; preeclampsia before 20 weeks

Preeclampsia before 20 weeks is not normal preeclampsia — it points to a molar pregnancy. That detail is asked directly.

🩺 After evacuation

  • Serial hCG levels for a full year — they must fall to zero and stay there
  • Reliable contraception for that year

She must not become pregnant for a year. A rising hCG is the marker for choriocarcinoma - and a new pregnancy would raise hCG and hide it.

Molar pregnancy carries a real risk of choriocarcinoma, which is why the follow-up is so strict.

🎯 NCLEX traps

  • Shoulder pain = ruptured ectopic
  • Very high hCG + uterus large for dates + no fetal heart = mole
  • No pregnancy for one year after a mole, with monthly hCG
  • Preeclampsia before 20 weeks suggests a mole
  • RhoGAM after any early pregnancy loss if Rh negative
Sources. Written from NICHD, CDC Reproductive Health, MedlinePlus and OpenStax A&P 2e (CC BY 4.0).