Preterm complications are all about organs that had not finished. RDS, NEC, and the signs of respiratory distress.
Every preterm complication traces back to an organ that had not finished developing. Lungs without surfactant, a gut without reliable blood flow, eyes still growing vessels, a brain with fragile capillaries.
| Complication | Because | Watch for |
|---|---|---|
| RDS | No surfactant before ~34–36 weeks | Grunting, nasal flaring, retractions, tachypnoea, cyanosis |
| NEC | Gut ischemia | Distended abdomen, bloody stool, feeding intolerance, bilious vomit |
| Retinopathy of prematurity | Immature retinal vessels + oxygen | Careful oxygen titration; eye screening |
| IVH | Fragile brain capillaries | Bulging fontanelle, apnea, falling tone, seizures |
| Hypothermia | Little fat, large surface area | Temperature instability |
| Hypoglycemia | Poor glycogen stores | Jitteriness, poor feeding, lethargy |
Grunting is the newborn trying to hold the alveoli open against collapse. It is never normal and always reported.
Acrocyanosis is normal. Central cyanosis of the lips, tongue and trunk is not.
Ischemic bowel that becomes necrotic and can perforate. Risk rises with prematurity, formula feeding and hypoxic events.
In suspected NEC, stop all feeds immediately and report. Feeding an ischemic gut makes it worse. Expect NPO, an orogastric tube for decompression, antibiotics and IV nutrition.
Breast milk is protective — a real teaching point for mothers of preterm infants.
Large baby, low sugar. Maternal glucose crossed; the baby’s pancreas overproduced insulin. At birth the glucose stops but the insulin does not.
Withdrawal in a baby exposed to opioids in utero: high-pitched cry, jitteriness, poor feeding, sneezing, sweating, loose stools, difficulty settling.
Bilirubin is fat-soluble and the newborn liver cannot conjugate it fast enough. Phototherapy changes its shape so it can leave in stool and urine without the liver. That is why feeding is half the treatment — nothing leaves if nothing moves through the gut.
Timing decides everything: jaundice before 24 hours is pathologic (hemolysis — Rh or ABO incompatibility, infection). After 24 hours, usually day 2–3, is physiologic.
| Do | Why |
|---|---|
| Change the position every 2–3 hours | Only the skin facing the light is being treated. Rotating exposes all of it, and it prevents pressure areas on a baby who is lying still |
| Naked except for a diaper, eyes covered | Maximum skin exposed; the mask protects the retina |
| Take the mask off every 4 hours | Check for corneal irritation, drainage and pressure — and let the parents see the baby’s face |
| Feed 8–12 times a day, breast milk or formula | Stool is the exit route. More feeds, more stools, faster clearance |
| Temperature every 4 hours; monitor fluid balance | The lights both overheat and dry out; watch for dehydration |
| Turn the lights off before drawing a bilirubin | Light degrades bilirubin in the sample and gives a falsely low result |
Do not put lotion, oil, cream or powder on the skin. Under phototherapy they can burn. Bathe with plain water only.
Do not supplement with water or glucose water. It does not lower bilirubin — it fills the baby up so it takes less milk, makes fewer stools, and the level goes up. Extra milk is the answer, never extra water.
| Expected — keep going | Report |
|---|---|
| A fine maculopapular rash | Bilirubin still climbing after 4–6 hours |
| Bronze discoloration of the skin | Signs of dehydration — sunken fontanelle, few wet diapers |
| Loose, greenish, frequent stools | Temperature instability |
| A sleepy baby who needs waking to feed | Lethargy, hypotonia, arching, a high-pitched cry |
A fine rash is not a reason to stop the lights. That is a wrong answer written to look cautious. The one thing on the right-hand list you must never sit on is the last row — that is acute bilirubin encephalopathy, and the stage after it, kernicterus, is permanent.