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🩺 NUR198 Exam 5 Deep Dive — Gastrointestinal Disorders

Modules 11 & 12 · Upper GI + Lower GI · Built from your Summer 2026 Key Concepts list

Click any topic to open it. One at a time = less overwhelm.
📝 Completed Guided Notes & Workbook — every blank filled in, with a hide-to-quiz button
🟣 Module 11 · Upper GI Notes →
GERD · gastritis · PUD · H. pylori · gastrectomy · dumping
🔵 Module 12 · Lower GI Workbook →
IBD/Crohn/UC · appendicitis · diverticulitis · obstruction · ostomies + 24-Q challenge

🟣 Module 11 · Procedures: Scopes & Tubes

EGD · NG tube placement · Enteral feeding (G-tube, J-tube)

Esophagogastroduodenoscopy (EGD)

WhatScope through mouth to view esophagus, stomach, duodenum. Dx tool for GERD, PUD, Barrett, bleeding, cancer (biopsy).

BeforeNPO 8 hrs. Consent. Remove dentures. Sedation (midazolam/propofol) + throat spray.

AfterNPO until gag reflex returns — this is THE test answer. Then monitor for perforation.

Red flags = perforation: fever, chest/shoulder pain, dysphagia, subcutaneous emphysema (crepitus in neck), bleeding. Report immediately.
Test trap: Sore throat after EGD is expected (throat lozenges OK once gag returns). Fever/pain is not.
NG Tube Placement & Care

UsesDecompression (suction), feeding, med administration, lavage.

  • Insertion: High Fowler's, measure nose→earlobe→xiphoid (NEX), hyperextend neck to pass nares, then flex chin to chest and sip water as tube passes to esophagus.
  • Verify placement: Gold standard = X-ray before first use. Ongoing: gastric pH ≤ 5, aspirate appearance. Auscultating air ("whoosh") is NOT acceptable.
  • Coughing, choking, cyanosis during insertion = tube in airway → pull back immediately.
  • Keep HOB ≥ 30° (feeding: 30–45° during and 30–60 min after).
  • Check residuals and pH per policy; flush with 30 mL water before/after meds and feeds.
Suction NG (decompression): monitor for metabolic alkalosis + hypokalemia from losing gastric acid. I&O is critical.
Enteral Feeding (G-tube / J-tube / NG)

WhoFunctional GI tract but can't swallow safely (stroke, head/neck cancer, ventilated). G-tube = stomach; J-tube = jejunum (use when stomach must be bypassed, ↓ aspiration risk).

  • #1 priority = prevent aspiration: HOB 30–45°, check placement + residual before feeds, hold per policy for high residual.
  • Flush 30 mL water q4h (continuous) and before/after everything.
  • Change bag/tubing q24h; hang time for open-system formula ≤ 4–8 hrs (prevents bacterial growth).
  • Diarrhea = most common complication (rate too fast, cold formula, contamination, hyperosmolar formula).
  • Stoma care: clean, dry, assess for skin breakdown and buried bumper.
Test trap: Sudden coughing/dyspnea/↓SpO₂ during a feed → STOP the feeding first, then position, suction, notify.

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Infographic · GI Pathophysiology — Key Terms

🟣 Module 11 · Oral Cavity & Neck

Dental caries · Salivary disorders · Oropharyngeal cancer · Neck dissection

Dental Caries & Salivary Disorders

CariesTooth decay from bacterial plaque + sugar → acid erosion. Prevention teaching = brush/floss, fluoride, limit sugar, routine dental visits.

SialadenitisInflammation/infection of a salivary gland (often S. aureus), commonly parotid in dehydrated/older/post-op clients. S/s: painful swollen gland, ↑ with eating.

CareHydration, warm compresses, gland massage, sialagogues (lemon drops/sour candy to stimulate flow), good oral hygiene, antibiotics.

Prevention win: Adequate hydration + oral care prevents parotitis in at-risk hospitalized clients.
Oropharyngeal Cancer & Neck Dissection

RisksTobacco (all forms), alcohol, HPV, sun exposure (lip). Combined tobacco + alcohol is synergistic.

S/sNon-healing mouth sore, white/red patch (leukoplakia/erythroplakia), lump, sore throat, dysphagia, hoarseness, unilateral ear pain.

Post-op neck dissection

  • Airway is the #1 priority — edema can obstruct; keep HOB up (semi-Fowler's) to reduce swelling and improve drainage.
  • Monitor flaps/drains; assess for carotid rupture risk (a late emergency — if it ruptures, apply pressure and call for help).
  • Communication plan (may not be able to speak), nutrition (often enteral), suction available.
Emergency: Sudden bright-red bleeding from the neck wound = possible carotid artery rupture → apply direct pressure, stay with client, call rapid response.

🟣 Module 11 · Esophageal Disorders

Esophageal obstruction · Hiatal hernia · GERD · Barrett esophagus · Esophageal cancer

GERD & Hiatal Hernia

PathoWeak/incompetent lower esophageal sphincter (LES) lets acid reflux into esophagus. Hiatal hernia = stomach herniates up through the diaphragm, worsening reflux.

S/sHeartburn (pyrosis), regurgitation, dyspepsia, worse lying down/after meals; may mimic chest pain.

Teaching (huge on exams)

  • Small frequent meals; stay upright 2–3 hrs after eating; elevate HOB on blocks for sleep.
  • Avoid triggers: caffeine, chocolate, peppermint, fatty/fried/spicy foods, alcohol, tobacco.
  • Avoid eating 3 hrs before bed; lose weight; avoid tight clothing.
  • Meds: antacids, H2 blockers (famotidine), PPIs (omeprazole — take before meals).
Test trap: Untreated chronic GERD → Barrett esophagus (metaplasia) → ↑ risk of esophageal adenocarcinoma. Barrett needs surveillance EGD.
Esophageal Cancer & Obstruction

RisksChronic GERD/Barrett, smoking, alcohol, obesity (adenocarcinoma); tobacco/alcohol (squamous cell).

Hallmark S/sProgressive dysphagia (solids → then liquids) + unintentional weight loss. Often late diagnosis.

CareNutrition support (soft/enteral), aspiration precautions, upright with meals, small bites, emotional support. Post-esophagectomy: HOB up, monitor for leak, respiratory care.

Report: New/worsening dysphagia, odynophagia, or weight loss should always be worked up — don't assume it's "just reflux."

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Infographic · GERD
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Infographic · Hiatal Hernia

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GERD — healthy vs. reflux
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Anti-reflux anatomy — LES & crural diaphragm
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Dyspepsia / reflux overview
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Barrett's esophagus (endoscopic)
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Barrett's esophagus — metaplasia
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Esophageal adenocarcinoma (gross specimen)

🟣 Module 11 · Stomach Disorders

PUD (gastric vs duodenal) · Gastritis · Gastric cancer/gastrectomy · Pernicious anemia · Dumping syndrome

Peptic Ulcer Disease — Gastric vs Duodenal ⭐

CausesH. pylori and NSAIDs are the top two. Also smoking, alcohol, stress, steroids.

Gastric ulcerDuodenal ulcer
Pain timingWITH/soon after eating (food ↑ pain)2–3 hrs after meals / at night; food relieves pain
WeightWeight loss (afraid to eat)Weight stable/gain
BleedingHematemesis more commonMelena more common

Care/MedsPPIs, H2 blockers, antibiotics for H. pylori (triple therapy), avoid NSAIDs/irritants, stop smoking.

Complications = emergencies: Hemorrhage (hematemesis, melena, ↓BP, ↑HR) and perforation (sudden severe pain, rigid board-like abdomen, rebound tenderness → surgical emergency, NPO, prep for OR).
Gastritis, Gastric Cancer & Gastrectomy

GastritisInflammation of gastric mucosa (H. pylori, NSAIDs, alcohol, stress). Acute → pain, N/V; chronic → can cause B12 malabsorption.

Gastric cancerOften vague/late: early satiety, indigestion, weight loss, anemia. Risks: H. pylori, chronic gastritis, smoked/salted foods, smoking.

Post-gastrectomyMonitor for bleeding, ensure NG patency (do NOT reposition NG after gastric surgery without order), pain control, nutrition, and the two classic complications below.

Pernicious anemia: Loss of intrinsic factor (parietal cells) → can't absorb B12 → needs lifelong B12 injections. Watch for neuro symptoms (paresthesias, balance).
Dumping Syndrome ⭐ (teaching-heavy)

PathoAfter gastric surgery, food dumps rapidly into small intestine → fluid shift. Early (15–30 min): dizziness, tachycardia, diaphoresis, cramping, diarrhea. Late (1–3 hr): rebound hypoglycemia.

Diet teaching (memorize)

  • Small, frequent meals; high protein, high fat, low simple carbs.
  • NO fluids WITH meals — drink between meals (30–60 min before/after).
  • Lie down after eating (recumbent/left side) to slow gastric emptying.
  • Avoid concentrated sweets.
Memory hook: Dumping teaching is the opposite of what feels natural — lie down, don't drink with meals, avoid sugar.

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Infographic · Peptic Ulcer Disease
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Infographic · Gastritis
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Infographic · Dumping Syndrome

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Stomach anatomy
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Gastric regions & secretions
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Gastric vs. duodenal ulcer
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H. pylori — Giemsa & Warthin–Starry stains
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Gastritis types — autoimmune vs. bacterial
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Pyloric stenosis (projectile vomiting)

🔵 Module 12 · Colonoscopy & Parenteral Nutrition

Colonoscopy prep/after · TPN safety rules

Colonoscopy

WhatScope of the entire large intestine. Screening (CRC), evaluate bleeding/IBD/polyps, biopsy/remove polyps.

PrepClear liquids day before (no red/purple), bowel prep (PEG/GoLYTELY) until stool runs clear, NPO after midnight, consent, sedation.

AfterMonitor VS + return of gag/alertness, expect flatus/cramping (air insufflation — walking helps), check for rectal bleeding, resume diet when alert.

Report perforation: severe abdominal pain/distension, rigid abdomen, fever, rectal bleeding beyond a small amount, ↓BP/↑HR.
Test trap: During acute diverticulitis, colonoscopy is contraindicated (perforation risk) — do it later, after inflammation resolves.
Parenteral Nutrition / TPN ⭐ (safety rules)

WhatIV nutrition when the gut can't be used. TPN = hypertonic (high dextrose) → needs a central line. PPN = lower concentration, peripheral, short-term.

  • Dedicated line — nothing else infused with TPN; verify with 2 nurses per policy.
  • Change bag and tubing q24h (high infection/glucose risk); use aseptic technique.
  • Monitor blood glucose regularly (hyperglycemia common; sliding-scale insulin often ordered).
  • Infuse via pump; never speed up or slow down to "catch up."
  • Daily weights, I&O, electrolytes; monitor for refeeding syndrome (↓K, ↓phos, ↓Mg).
If the next bag is late/unavailable: hang D10W (or per policy) to prevent rebound hypoglycemia — never abruptly stop TPN.
Air embolism risk (central line): clamp line, place client left side, Trendelenburg, give O₂, call provider.

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Infographic · TPN & Enteral Feeding

🔵 Module 12 · Functional & Malabsorption + Bowel Habits

IBS · Celiac disease · Constipation · Diarrhea · Fecal incontinence

Irritable Bowel Syndrome (IBS)

PathoFunctional disorder — altered motility + visceral hypersensitivity, no structural/inflammatory damage. Triggers: stress, certain foods, hormones.

S/sChronic abdominal pain relieved by defecation, bloating, alternating diarrhea/constipation. No bleeding, no weight loss, no fever (those suggest something else).

TeachingIdentify/avoid trigger foods (food diary), low-FODMAP diet, adequate fiber + fluids, regular exercise, stress management. Meds target the dominant symptom (antispasmodics, antidiarrheals, laxatives).

Key distinction: IBS = functional (no damage). IBD (Crohn/UC) = inflammatory with real tissue damage, bleeding, systemic signs.
Celiac Disease

PathoAutoimmune reaction to gluten (wheat, barley, rye) damages small-intestine villi → malabsorption.

S/sSteatorrhea (fatty, foul, floating stools), bloating, weight loss, fatigue, anemia, vitamin deficiencies; kids: failure to thrive. Dermatitis herpetiformis (itchy rash).

TeachingLifelong strict gluten-free diet is the only treatment. Read labels (hidden gluten), watch cross-contamination. Safe grains: rice, corn, quinoa, oats (certified GF).

Test trap: Symptoms resolve only with complete gluten avoidance — "cutting back" isn't enough; even small amounts damage villi.
Constipation, Diarrhea & Fecal Incontinence

Constipation↑ fiber (gradually), ↑ fluids, ↑ activity, respond to urge, scheduled toileting. Laxative overuse and chronic straining cause problems (hemorrhoids, Valsalva).

DiarrheaPriority = fluid/electrolyte balance (watch dehydration, hypokalemia), skin care, identify cause (infection, C. diff, meds, feeding). For C. diff: contact precautions + soap-and-water handwashing (alcohol gel doesn't kill spores).

Fecal incontinenceBowel training/scheduled toileting, skin protection/barrier cream, dignity + emotional support, treat underlying cause.

Watch: Severe/prolonged diarrhea → hypovolemia + hypokalemia (metabolic acidosis) — monitor K⁺ and cardiac rhythm.

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Infographic · Irritable Bowel Syndrome
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Infographic · Celiac Disease
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Villous atrophy — celiac histology

🔵 Module 12 · Acute Inflammatory Abdomen

Appendicitis · Peritonitis · Diverticular disease

Appendicitis ⭐

S/sPeriumbilical pain that migrates to RLQ (McBurney's point), rebound tenderness, low-grade fever, N/V, anorexia. Rovsing/psoas signs.

CareNPO, IV fluids, prep for appendectomy. Position of comfort (often right side/knees flexed).

NO heat, NO enemas, NO laxatives — they can rupture the appendix. Sudden relief of pain = rupture → then diffuse pain returns = peritonitis. Report immediately.
Peritonitis

PathoInflammation of the peritoneum from perforation/leak (ruptured appendix, diverticulum, ulcer, bowel). Life-threatening — can lead to sepsis + shock.

S/sRigid, board-like abdomen, severe diffuse pain, rebound tenderness, absent bowel sounds, fever, tachycardia, ↓BP, shallow breathing.

CareNPO, NG decompression, IV fluids + antibiotics, monitor for shock, prep for surgery. Semi-Fowler's to localize/pool drainage in pelvis.

Priority: Recognize sepsis/shock early — fluids, antibiotics, and source control (surgery) are urgent.
Diverticulosis vs Diverticulitis ⭐ (opposite diets)

DiverticulosisOutpouchings in the colon wall, usually asymptomatic. Linked to low-fiber diet + chronic constipation/straining.

DiverticulitisThose pouches become inflamed/infected. S/s: LLQ pain, fever, ↑WBC, N/V, altered bowel habits.

StateDiet
Diverticulosis (prevention)HIGH fiber, high fluids to prevent flares
Acute diverticulitisLOW fiber / clear liquids → bowel rest (NPO if severe), then advance
During acute diverticulitis: NO colonoscopy, NO enemas, NO high fiber (perforation risk). Watch for perforation/peritonitis.
Memory hook: Diverticulosis = fiber ON. Diverticulitis = fiber OFF (rest the bowel), then rebuild fiber once healed.

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Infographic · Appendicitis
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Infographic · Diverticulitis & Diverticulosis
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Peritonitis
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Diverticulitis — causes & features

🔵 Module 12 · Inflammatory Bowel Disease (IBD) ⭐⭐

Crohn disease vs Ulcerative colitis — highest-yield compare

Crohn Disease vs Ulcerative Colitis — Compare Table
Crohn DiseaseUlcerative Colitis
LocationMouth → anus, anywhere; often terminal ileum. Skip lesionsColon & rectum only, continuous from rectum up
DepthFull thickness (transmural) → "cobblestone"Mucosa/submucosa only
StoolDiarrhea, usually non-bloody, steatorrheaBloody diarrhea w/ mucus, many stools/day
ComplicationsFistulas, strictures, abscess, malabsorptionToxic megacolon, ↑ colon cancer risk, perforation
CureNo surgical cure (can recur)Colectomy can be curative

Shared careMonitor fluid/electrolytes + nutrition (may need TPN in flares), skin/perianal care, meds: aminosalicylates (mesalamine), corticosteroids (flares), immunomodulators, biologics. Low-residue diet in flares; avoid triggers.

UC emergency — toxic megacolon: distended/tender abdomen, fever, tachycardia, ↓bowel sounds → risk of perforation. Report immediately.
Memory hook: Crohn = Cobblestone, skip lesions, Complications (fistulas), whole tract. UC = Ulcers Continuous, in the Colon, bloody stool, Cured by colectomy.

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Infographic · Crohn's vs UC — Patho, Signs & Causes
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Infographic · Crohn's vs UC — Treatments & Complications
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Toxic Megacolon
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Megacolon — surgical view

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Crohn's ileitis — inflammation, stenosis & fistula
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Ulcerative colitis — endoscopic (normal vs. UC)

🔵 Module 12 · Obstruction · Cancer · GI Bleed

Bowel obstruction (SBO vs LBO) · Colorectal cancer · GI bleed

Bowel Obstruction (SBO vs LBO)

PathoBlockage of intestinal contents. Mechanical (adhesions #1 for SBO, tumors, hernia, volvulus) or functional (paralytic ileus).

Small bowel (SBO)Large bowel (LBO)
VomitingEarly, profuse (may be bilious/fecal)Late or absent
DistensionLessMarked
PainCramping, higherLower, more gradual
Bowel soundsHigh-pitched then absentAbsent (later)

CareNPO + NG decompression, IV fluids + electrolyte replacement, I&O, monitor for strangulation/perforation, prep for surgery if mechanical.

SBO fluid loss: vomiting → metabolic alkalosis + hypovolemia. Fever, ↑ pain, ↑HR, ↓BP = strangulation → surgical emergency.
SBO (mechanical) vs Paralytic Ileus (functional) ⭐

PathoBoth stop intestinal contents from moving — the difference is why. SBO = a physical blockage. Ileus = peristalsis simply stops (no blockage).

Mechanical SBOParalytic (adynamic) ileus
CausePhysical block: adhesions (#1), hernia, tumor, volvulus, intussusceptionNo block: post-op (most common), peritonitis, hypokalemia, opioids, sepsis, bowel handling during surgery
Bowel soundsHigh-pitched / hyperactive above the block → later absentAbsent or ↓ throughout (no peristalsis)
PainCramping, colicky — comes in wavesDiffuse, constant, milder discomfort
DistensionYesYes (often marked)
VomitingYes — may become bilious/fecalPossible, usually less
OnsetCan be acuteOften after abdominal surgery (expected ~24–72h; concerning if longer)
TreatmentNPO + NG decompression, IV fluids/electrolytes; surgery if strangulation or complete blockTreat the cause: NPO + NG, IV fluids, correct K⁺, limit opioids, early ambulation; usually resolves without surgery

NursingSBO → watch for strangulation (fever, ↑pain, ↑HR, ↓BP, rigid abdomen) = surgical emergency. Ileus → ambulate, monitor for return of bowel sounds & passing flatus (sign it’s resolving).

MemoryMechanical = hyperactive then silent + crampy. Ileus = silent + constant & dull. Hypokalemia and opioids are the classic ileus causes.

Colorectal Cancer (CRC)

RisksAge >50, family hx, IBD (esp. UC), high-fat/low-fiber diet, processed/red meat, smoking, obesity, polyps.

S/sChange in bowel habits, blood in stool (occult or visible), narrow/pencil stools (left-sided), anemia/fatigue (right-sided), unexplained weight loss.

Screening/DxColonoscopy (gold standard, removes polyps), FOBT/FIT, CEA tumor marker (trend, not screening).

CareSurgery ± chemo/radiation; may create colostomy; nutrition + emotional/ostomy support.

Teaching: Screening colonoscopy at 45 (average risk), high-fiber/low-fat diet, don't ignore rectal bleeding or bowel-habit changes.
GI Bleed

Upper GI bleedHematemesis (bright red or coffee-ground) and/or melena (black tarry). Sources: PUD, varices, gastritis, Mallory-Weiss.

Lower GI bleedHematochezia (bright red rectal blood). Sources: diverticulosis, CRC, hemorrhoids, IBD, angiodysplasia.

Priorities (ABC)Assess for shock (↑HR, ↓BP, pallor, ↓LOC), 2 large-bore IVs + fluids/blood, O₂, NPO, type & cross, monitor H&H, prep for endoscopy/scope to locate + treat.

Priority: Airway/breathing/circulation and hemodynamic stability come first — stop the bleed and restore volume before anything else.

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Infographic · GI Bleed
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Infographic · Small Bowel Obstruction
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Infographic · Colon & Esophageal Cancer

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Ileus vs. small bowel obstruction
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Bowel obstruction — presentation & management
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Paralytic ileus vs. normal (X-ray)
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Abdominal X-ray (KUB)
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Intussusception
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Volvulus — 'corkscrew' sign
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Hirschsprung disease (failure to pass meconium)

🔵 Module 12 · Anorectal & Hernias

Hemorrhoids · Anal fistula · Pilonidal cyst · Abdominal hernia

Hemorrhoids, Anal Fistula & Pilonidal Cyst

HemorrhoidsDilated rectal veins (straining, pregnancy, constipation, prolonged sitting). S/s: bright-red bleeding with defecation, pain, itching. Care: high fiber + fluids, sitz baths, topical agents, don't strain; hemorrhoidectomy if severe.

Anal fistulaAbnormal tract between anal canal and skin (often after abscess/abscess in IBD). S/s: drainage, pain, irritation. Care: surgery (fistulotomy), sitz baths, wound/skin care.

Pilonidal cystCyst/abscess in the sacrococcygeal cleft (hair follicle). Care: I&D, packing, hygiene, keep area clean/dry, wound care teaching.

Shared post-opSitz baths for comfort/healing, high-fiber diet + stool softeners (avoid straining), pain control, monitor for bleeding/infection.

Abdominal Hernia

PathoProtrusion of organ/tissue through a weak abdominal wall (inguinal, umbilical, incisional). Reducible = pushes back in; incarcerated = stuck; strangulated = blood supply cut off (emergency).

CareAvoid heavy lifting/straining, treat constipation/cough; surgical repair (herniorrhaphy). Post-op: avoid lifting, support incision when coughing, monitor bowel function.

Strangulation: severe pain, firm/tender non-reducible bulge, N/V, no flatus/stool, signs of obstruction → surgical emergency.

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Anorectal fistula
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Hernia anatomy — hernial sac

🔵 Module 12 · Ostomies

Ileostomy vs Colostomy · Stoma care

Ileostomy vs Colostomy & Stoma Care
IleostomyColostomy
LocationSmall intestine (ileum), usually RLQColon; more distal = more formed stool
OutputLiquid, constant, enzyme-rich (skin-damaging)More formed/solid (esp. left colon)
RisksDehydration + electrolyte loss, skin breakdownFewer fluid issues

Stoma assessmentHealthy stoma = pink/red, moist. Pale = poor perfusion; dark/purple/black = ischemia/necrosis → report immediately. Small amount of bleeding when cleaning is normal.

Care/teachingSkin barrier fits snugly (protect peristomal skin), empty pouch when ⅓–½ full, change appliance q3–7 days. Ileostomy: ↑ fluids + electrolytes, chew well, watch for blockage (avoid high-fiber/stringy foods early). Odor/gas control, emotional support + body image.

Report: stoma turning dusky/black, no output + cramping/distension (possible blockage), or signs of dehydration with an ileostomy.

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🟡 Exam Tips & Highest-Yield Recall

Quick-fire answers most likely to show up

⚡ The 10 things most likely to be tested
  • Crohn vs UC — location, stool, complications, cure (know the table cold).
  • Gastric vs duodenal ulcer — pain timing vs meals; hematemesis vs melena.
  • PUD complications — hemorrhage & perforation (rigid abdomen = surgical emergency).
  • Dumping syndrome — lie down after meals, no fluids with meals, low simple carb/high protein.
  • TPN rules — dedicated line, tubing/bag q24h, monitor glucose, hang D10 if bag is late, air-embolism response.
  • Enteral feeding priorities — verify placement, HOB 30–45°, aspiration prevention, residuals.
  • Appendicitis — RLQ/McBurney's; sudden pain relief = perforation. NO heat/enemas/laxatives.
  • Bowel obstruction — SBO vs LBO; NPO + NG decompression; metabolic alkalosis from vomiting.
  • Diverticulosis vs diverticulitis — opposite diets; NO colonoscopy/enema during acute flare.
  • Post-gastrectomy — pernicious anemia (lifelong B12), dumping syndrome.
🧪 Acid-base & electrolyte quick map
  • Vomiting / NG suction → lose acid → metabolic alkalosis + hypokalemia.
  • Diarrhea / ileostomy → lose bicarb → metabolic acidosis + hypokalemia + dehydration.
  • Prolonged obstruction → fluid shifts, hypovolemia; watch K⁺ and cardiac rhythm.
🚨 "Call the provider NOW" red flags
  • Rigid, board-like abdomen + rebound tenderness = perforation/peritonitis.
  • Sudden relief of appendicitis pain = rupture.
  • Dusky/black stoma = ischemia.
  • UC + distended abdomen/fever/tachycardia = toxic megacolon.
  • Hematemesis/melena + ↓BP/↑HR = GI hemorrhage/shock.
  • Neck-wound bright-red bleeding post-dissection = carotid rupture.

💊 Medications

High-yield GI drugs for Exam 5 (Modules 11 & 12), grouped by what they do — action, use, and the nursing/teaching points most tested

🔥 Reduce or Neutralize Acid & Protect the Ulcer

Omeprazole / PantoprazolePPI

Use: GERD, PUD, gastritis, H. pylori, stress-ulcer prevention.

Key points: Blocks the gastric proton pump — the final step of acid production. Take 30–60 min before meals; don't crush delayed-release forms.

Watch: Long-term use: ↓ magnesium, ↓ B12, ↑ fracture & C. diff risk.

FamotidineH2 Blocker

Use: GERD, PUD, heartburn.

Key points: Blocks histamine-2 receptors on parietal cells to reduce acid. Slower, gentler than PPIs; can be scheduled or PRN.

Aluminum / Magnesium / Calcium antacidsAntacid

Use: Fast, short-term heartburn & dyspepsia relief.

Key points: Neutralize acid already in the stomach. Separate from other meds by 1–2 hr (they impair absorption).

Watch: Aluminum → constipation; magnesium → diarrhea; calcium → rebound acid.

Sucralfate (Carafate)Mucosal Protectant

Use: PUD — coats and protects the ulcer.

Key points: Forms a protective barrier over the ulcer base. Give on an empty stomach, 1 hr before meals and at bedtime.

Watch: Separate from antacids/other meds by ≈ 30 min; can cause constipation.

Clarithromycin + Amoxicillin + PPIH. pylori Triple Therapy

Use: Eradicate H. pylori in PUD/gastritis.

Key points: Two antibiotics kill the bacteria; the PPI lowers acid so they work. Bismuth + metronidazole may be added (quad therapy).

Watch: Finish the entire course even when feeling better, or it recurs.

🔄 Move the Gut & Stop Nausea (Motility & Antiemetics)

Metoclopramide (Reglan)Prokinetic / Antiemetic

Use: Gastroparesis, GERD, nausea, dumping-related symptoms.

Key points: Speeds gastric emptying and raises LES tone. Give before meals and at bedtime.

Watch: Extrapyramidal symptoms / tardive dyskinesia — watch for tremor, restlessness, abnormal movements.

Ondansetron (Zofran)5-HT3 Antiemetic

Use: Nausea and vomiting.

Key points: Blocks serotonin (5-HT3) receptors in the CTZ and gut. Common first-line antiemetic.

Watch: Can prolong the QT interval; watch for headache and constipation.

Promethazine (Phenergan)Antiemetic (Antihistamine)

Use: Nausea and vomiting.

Key points: Blocks H1 and dopamine receptors. Very sedating.

Watch: IV extravasation causes severe tissue damage — give slowly, deep IM/central preferred; drowsiness.

🛑 Slow the Gut Down (Antidiarrheals & Antispasmodics)

Loperamide (Imodium)Antidiarrheal

Use: Acute and chronic diarrhea (non-infectious).

Key points: Slows intestinal motility so more water is reabsorbed. Not for the child or the patient with bloody stool/fever.

Watch: Avoid in C. diff or infectious diarrhea — trapping toxin can cause toxic megacolon.

Diphenoxylate / Atropine (Lomotil)Antidiarrheal

Use: Diarrhea control.

Key points: Opioid-derived; slows motility. Atropine added to discourage misuse.

Watch: Anticholinergic effects; controlled substance; caution with IBD flares.

Dicyclomine (Bentyl)Antispasmodic

Use: IBS — cramping and abdominal pain.

Key points: Anticholinergic that relaxes GI smooth muscle to ease spasm.

Watch: Anticholinergic effects: dry mouth, blurred vision, urinary retention, constipation.

🌿 Get Things Moving (Laxatives & Bowel Prep)

Psyllium (Metamucil)Bulk-Forming Laxative

Use: Constipation; safest for long-term/daily use; also IBS.

Key points: Absorbs water to add soft bulk and stimulate peristalsis. Take with a full glass of water.

Watch: Too little fluid can cause esophageal/bowel obstruction.

Docusate (Colace)Stool Softener

Use: Prevent straining (post-op, MI, hemorrhoids, opioids).

Key points: Draws water into stool to soften it. First-line prophylaxis with opioids.

Watch: Softener, not a strong stimulant — for prevention, not acute disimpaction.

Polyethylene glycol (MiraLAX / GoLYTELY)Osmotic Laxative

Use: Constipation; bowel prep before colonoscopy.

Key points: Pulls water into the bowel. For prep, drink until stool runs clear yellow liquid.

Watch: Monitor fluid/electrolyte balance with large prep volumes.

LactuloseOsmotic Laxative

Use: Constipation (and lowers ammonia in hepatic encephalopathy).

Key points: Osmotic draw of water into the colon; acidifies stool.

Watch: Titrate to 2–3 soft stools/day; causes bloating/flatus.

Bisacodyl / SennaStimulant Laxative

Use: Short-term constipation, bowel prep.

Key points: Directly stimulate peristalsis. Fast-acting but for short-term use.

Watch: Not for daily long-term use — dependence and cramping.

🛡️ Calm Inflammation (IBD Therapy)

Mesalamine / SulfasalazineAminosalicylate (5-ASA)

Use: IBD — maintain remission in UC & Crohn.

Key points: Anti-inflammatory action on the bowel mucosa. Maintenance drug (not for acute rescue).

Watch: Sulfasalazine: give with food + fluids, may turn urine orange; sulfa allergy caution.

PrednisoneCorticosteroid

Use: IBD acute flares (short-term).

Key points: Powerful anti-inflammatory to calm a flare. Use the lowest dose for the shortest time; taper, never stop abruptly.

Watch: ↑ glucose, infection risk, mood changes, osteoporosis, GI irritation — take with food.

AzathioprineImmunomodulator

Use: IBD — steroid-sparing maintenance.

Key points: Suppresses the immune response to reduce inflammation. Slow onset (weeks–months).

Watch: Bone-marrow suppression & infection — monitor CBC; report fever/sore throat.

Infliximab (Remicade)Biologic (anti-TNF)

Use: Moderate–severe IBD.

Key points: Monoclonal antibody that blocks TNF-alpha. Given by IV infusion.

Watch: Screen for TB & hepatitis before starting; serious infection risk — hold if febrile/infected.

🦠 Fight Infection (Antibiotics)

Metronidazole (Flagyl)Antibiotic

Use: Diverticulitis, intra-abdominal infection, C. difficile.

Key points: Anti-anaerobic/antiprotozoal. Complete the full course.

Watch: No alcohol during and 3 days after — disulfiram-like reaction; metallic taste.

Vancomycin (oral)Antibiotic

Use: C. difficile infection (oral route acts locally in the gut).

Key points: Oral form stays in the GI tract to treat C. diff. Pair with contact precautions + soap-and-water hygiene.

Watch: Oral vanco is for C. diff (not absorbed) — different purpose than IV vanco.

💉 Replace What's Missing (Supplements)

Cyanocobalamin (Vitamin B12)Vitamin Supplement

Use: Pernicious anemia; post-gastrectomy.

Key points: Replaces B12 that can't be absorbed without intrinsic factor. Given as lifelong IM injections.

Watch: Oral B12 won't work without intrinsic factor — must be parenteral.

🎥 Video lectures

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▶ GI Medications — nursing relevance (animated)

📊 More visuals

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GI medicines — PPIs, H2 blockers & more
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H2 blockers — acid control
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Antibiotic name stems
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Antibiotic side effects

📌 Clinical Signs & Quick References

GI reference charts & screenshots, grouped. (Non-GI images like cardiac, respiratory, and general electrolyte physiology were left out.)

🩻 Abdominal Regions & Assessment

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Right Hypochondriac Region
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Epigastric Region
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Left Hypochondriac Region
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Right Lumbar Region
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Umbilical Region
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Left Lumbar Region
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Right Iliac (Inguinal) Region — Appendix
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Hypogastric (Pubic) Region
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Left Iliac (Inguinal) Region

🔎 Acute-Abdomen & Pancreatitis Signs

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Cullen Sign (periumbilical ecchymosis)
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Grey Turner Sign / retroperitoneal hemorrhage
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Clinical Signs — Disease · Sign · Key Features
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Acute Pancreatitis — classic signs & symptoms
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Acute Pancreatitis

🎥 Video lectures

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▶ Acute Pancreatitis — classic signs (animated)

🎯 Practice Quiz — 200 Questions

Multiple choice · select-all · matching · drop-down — every item has a rationale

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