NUR 198 · Exam 2 · Respiratory · the Framework

Respiratory I: Upper Respiratory Disorders Gas Exchange

the guided notes, filled in. Based on “Respiratory I: Gas Exchange — Nursing Management of Clients with Upper Respiratory Disorders.”

The BIG question of this module: Can the patient oxygenate effectively? If not — Why? · What assessment findings support that? · What should the nurse do first?
That is the clinical judgment thinking we are building all through NUR 198.
Every highlighted answer was a blank in the handout.
Basic Respiratory Assessment ReviewGas Exchange Overview — the 5 stepsVentilation vs OxygenationHypoxemia vs HypoxiaManifestations of HypoxiaWork of Breathing — Restrictive vs ObstructiveUpper Respiratory Infections (URIs)Prioritization PracticeObstructive Sleep Apnea (OSA)Respiratory Case Study #1EpistaxisLaryngeal Obstruction & Cancer of the LarynxNCLEX-Style QuestionsFinal Clinical Judgment Reminder
🩺 Basic Respiratory Assessment Review18 items

When assessing a respiratory patient, I should ALWAYS look at:

Show 5 moreHide these 5
  • Respiratory ratenormal adult 12–20/min; under 12 or over 20 needs a second look Count for a full minute if it is irregular.
  • Respiratory depthshallow vs deep — shallow breathing moves little air even at a normal rate
  • Respiratory effortrelaxed vs labored; is the patient working to breathe or is it effortless?
  • Work of breathingretractions, nasal flaring, tripod positioning, grunting, pursed-lip breathing
  • Lung soundsall fields front and back — clear, crackles, wheezes, stridor, diminished, or absent
Show 4 moreHide these 4
  • Oxygen saturation95–100% normally; 88–92% is the target in COPD/CO2 retainers
  • Skin colorpink vs pale, dusky, mottled, or cyanotic — cyanosis is a LATE sign
  • Mental status / LOCrestlessness, anxiety, and irritability come FIRST; confusion and somnolence come later
  • Use of accessory musclessternocleidomastoid and scalene use, intercostal retractions — a sign of real distress

The two that change first are respiratory rate and mental status. Saturation and skin color change late — do not wait for them.

💨 Gas Exchange Overview — the 5 steps32 items

Respiratory function is the body moving oxygen from the AIR into the CELLS. Five things have to work. Ask which one broke.

Step 1Ventilation — air moves in and out
Step 2Air reaches the alveoli
Step 3Gas exchange across the membrane
Step 4Oxygen binds hemoglobin
Step 5Perfusion delivers it to tissue

Step 1: Ventilation

Can the patient physically move air?

Examples of ventilation problems:

  • Opioid overdose or oversedation — the drive to breathe is suppressed
  • Neuromuscular disease — Guillain-Barre, myasthenia gravis, spinal cord injury
  • Chest wall or mechanical limits — flail chest, obesity, post-op pain and splinting

Poor ventilation causes: ↑CO2respiratory acidosis — pH falls, and the patient gets drowsy, headachy, then confused

Step 2: Air Reaches the Alveoli

Problems that interfere:

  • Secretions or mucus plugging
  • Bronchospasm and airway swelling (asthma, anaphylaxis)
  • Atelectasis, tumor, or a foreign body blocking the airway

Result: less oxygen available for exchange.

Step 3: Gas Exchange

Oxygen moves: from the alveolus into the pulmonary capillary blood, down its pressure gradient

Carbon dioxide moves: from the blood back into the alveolus, and out with exhalation

Conditions that impair gas exchange:

  • Pneumonia — the alveoli fill with exudate
  • Pulmonary edema — fluid widens the distance oxygen must cross
  • ARDS, pulmonary fibrosis, or emphysema — the membrane itself is damaged or destroyed

Step 4: Oxygen Binds to Hemoglobin

Even with perfect lungs, oxygen still needs a ride.

Problems:

  • Anemia or acute blood loss — not enough hemoglobin to carry oxygen
  • Carbon monoxide poisoning — CO binds hemoglobin far more tightly than oxygen does

Low hemoglobin can cause: tissue hypoxia even when SpO2 and PaO2 look normal — there are simply fewer carriers

Step 5: Perfusion

Perfusion problems:

  • Shock or hypotension — not enough pressure to deliver blood
  • Heart failure or low cardiac output
  • Pulmonary embolism — blood cannot reach ventilated alveoli

📊 BIG Picture

Respiratory problems usually come down to: poor air movement · blocked alveoli · impaired gas exchange · low hemoglobin · poor perfusion. Name which one before you pick an intervention.

🔄 Ventilation vs Oxygenation6 items

Two different failures. They are treated differently, so name which one you are looking at.

Ventilation — "move AIR"Oxygenation — "move OXYGEN"
Main problemCO2 retention — hypercapnialow oxygen in the blood — hypoxemia
What the labs show↑PaCO2 with a falling pH (respiratory acidosis)↓PaO2 and ↓SpO2, with PaCO2 often normal or low at first
ExamplesCOPD · opioid overdose · hypoventilationPulmonary edema · pneumonia · pulmonary embolism
Fix aimed athelping them move air — reverse the sedation, support ventilation, BiPAPimproving exchange — oxygen, treat the pneumonia or the edema

Oxygen alone does not fix a ventilation problem. If the patient is not moving air, giving more oxygen does not remove the CO2.

🩸 Hypoxemia vs Hypoxia8 items
HypoxemiaHypoxia
WhereLow oxygen in the BLOODLow oxygen at the TISSUE
Usually caused bya problem in the lung — V/Q mismatch, shunt, poor diffusion, or hypoventilationa problem with delivery or use — the lungs may be fine
Examplespneumonia · pulmonary edema · PE · atelectasis · COPD exacerbationanemia · carbon monoxide poisoning · shock or low cardiac output · severe hemorrhage

A patient can have normal lungs and still be hypoxic. That is the whole point of this section — anemia, carbon monoxide, and shock all starve tissue while the lungs look fine.

🧠 NCLEX clinical judgment thinking

When a patient deteriorates, ask which of the four broke:

  • Ventilation? Are they moving air?
  • Gas exchange? Is the membrane working?
  • Perfusion? Is blood getting there?
  • Hemoglobin? Is there anything to carry it?
🚨 Manifestations of Hypoxia5 items
Early signs — act hereLate signs — already in trouble
Restlessness · anxiety · irritability · tachypnea · tachycardia · mild hypertension · pallor Cyanosis · bradycardia · hypotension · dysrhythmias · confusion → somnolence → unresponsive

Cyanosis is a late sign. If you are waiting for it to confirm hypoxia, you waited too long.

Why does the body respond this way?

Tachycardia — why?

The heart speeds up to push the oxygen it does have around faster — a compensatory rise in cardiac output.

Tachypnea — why?

Chemoreceptors sense the falling oxygen and rising CO2 and drive faster breathing to blow off CO2 and pull in more oxygen.

Restlessness — why?

The brain is the most oxygen-sensitive organ in the body. Cerebral hypoxia shows up as restlessness and anxiety before anything else changes — which is exactly why a "difficult, agitated" patient may be hypoxic, not difficult.

💪 Work of Breathing — Restrictive vs Obstructive6 items
RestrictiveObstructive
ProblemDifficulty getting air INDifficulty getting air OUT
ExamplesPulmonary fibrosis · pneumonia · atelectasis · pleural effusion · obesity · kyphoscoliosis · neuromuscular diseaseCOPD — emphysema and chronic bronchitis · asthma
Expected findingsRapid shallow breathing · decreased lung volumes · decreased compliance · dyspnea on exertionProlonged expiratory phase · wheezing · air trapping and barrel chest · decreased FEV1/FVC

Restrictive = cannot fill. Obstructive = cannot empty.

🦠 Upper Respiratory Infections (URIs)39 items

URIs involve the nose, sinuses, pharynx, and larynx.

Most URIs are: viral

Because of this, antibiotics are: not indicated — they do nothing for a virus. Reserve them for a confirmed bacterial cause such as strep.

Common manifestations

  • Nasal congestion · rhinorrhea · sore throat · hoarseness · cough · fatigue · fever

URI nursing priorities

  • Maintain the airway — always first
  • Hydration to thin secretions
  • Reduce aspiration risk
  • Patient education
  • Prevent complications

🚨 URI RED FLAG findings — require immediate follow-up

  • Stridor — the upper airway is narrowing
  • Drooling or inability to swallow secretions
  • Muffled "hot potato" voice, or trouble speaking
  • Severe dyspnea, accessory muscle use, cyanosis, or a falling LOC

Rhinitis / Rhinosinusitis

Expected findings:

  • Nasal congestion and rhinorrhea
  • Facial pain and pressure over the sinuses, worse when bending forward
  • Postnasal drip, headache, reduced sense of smell

Why does sinus pressure occur? Swollen, inflamed mucosa blocks the sinus openings so mucus cannot drain. The sinus is a fixed bony box — trapped mucus has nowhere to go, so pressure builds.

Pharyngitis

Expected findings:

  • Sore throat and pain with swallowing
  • Red, inflamed pharynx, sometimes with fever

Findings concerning for strep:

  • Fever over 101 F
  • Tonsillar exudate (white patches)
  • Tender, swollen anterior cervical nodes — and notably no cough

Peritonsillar Abscess

Concerning findings: drooling · muffled voice · difficulty swallowing · trismus (cannot open the mouth).

Why is drooling concerning? It means the patient can no longer swallow their own saliva — the airway is being threatened. Keep them upright, do not put anything in the mouth, have suction and emergency airway equipment ready, and notify the provider now.

Laryngitis

Main manifestation: hoarseness or complete loss of the voice

Avoid: talking — and whispering, which strains the cords more than normal speech · smoking and irritants · alcohol and caffeine, which dry the throat

Encourage: voice rest · humidified air · plenty of fluids

URI complications

  • Airway obstruction · sepsis · meningitis · dysphagia · cellulitis · rebound congestion

Rebound congestion (rhinitis medicamentosa) comes from using topical decongestant sprays longer than 3 days — the vessels rebound wider than before, so the patient feels more congested and uses more spray.

⚖️ Prioritization Practice5 items

Which URI patient worries you MOST, and why?

FindingWhat it tells youRank
StridorThe upper airway is actively narrowing. This is an emergency now.1st
DroolingThe patient cannot handle their own secretions — obstruction is close behind.2nd
CyanosisA LATE sign. Hypoxia is already significant by the time you see it.3rd
ConfusionCerebral hypoxia — also late, and it means compensation is failing.4th
Accessory muscle useReal distress and increased work of breathing, but the airway is still open.5th

Airway beats everything. Stridor and drooling are both telling you the airway is closing. Cyanosis and confusion mean the hypoxia is already severe — they are late, not early.

😴 Obstructive Sleep Apnea (OSA)16 items

OSA involves repeated: episodes of upper airway collapse during sleep — the airway closes, breathing stops for 10 seconds or more, and the patient partially wakes to reopen it

This causes hypoxia, hypercapnia, and sympathetic stimulation over and over, all night.

Risk factors

  • Obesity and a large neck circumference (over 17 in for men, 16 in for women)
  • Male sex and increasing age; risk rises in women after menopause
  • Large tonsils, a receding jaw, or a crowded upper airway
  • Alcohol or sedatives at bedtime, and smoking

Manifestations

  • Loud snoring · daytime sleepiness · morning headaches · hypertension · gasping during sleep

Why do patients wake up exhausted? The repeated arousals fragment sleep. They never stay in deep or REM sleep long enough to restore anything — so a full night in bed still produces no real rest.

CPAP vs BiPAP

CPAPBiPAP
ProvidesONE continuous pressure, the same on inhale and exhaleTWO pressures — a higher one on inspiration (IPAP) and a lower one on expiration (EPAP)
PurposeSplints the airway open so it cannot collapseSplints the airway AND assists the breath, which also helps blow off CO2

Why may patients tolerate BiPAP better? Because exhaling against the lower pressure takes much less work. Breathing out against the single high CPAP pressure is what most people cannot stand.

OSA plus opioids is a dangerous combination. Both suppress the airway and the drive to breathe — that is the next case.

🏥 Respiratory Case Study #112 items

Important cues: obesity · large neck circumference · PCA morphine · post-op · increasing respiratory rate

What complication should the nurse anticipate? Opioid-induced respiratory depression, on top of very likely undiagnosed OSA. The obesity, the neck, and the morphine PCA all stack in the same direction.

Signs of respiratory decline

Apnea · bradypnea · cyanosis · somnolence · snorting or gasping respirations

What is the PRIORITY problem? Impaired gas exchange from opioid-induced respiratory depression with airway obstruction — an airway and breathing emergency.

Immediate nursing actions

  • Stop the opioid — stop the PCA
  • Stimulate the patient and open the airway — reposition, sit them up, head-tilt chin-lift
  • Apply oxygen and get continuous SpO2; be ready to bag-mask if breathing is inadequate
  • Call for help / rapid response, and have naloxone ready per order

Naloxone

Purpose: It is an opioid antagonist — it reverses the respiratory depression and sedation.

Risk of giving it: It reverses the analgesia too, so severe pain returns suddenly, and it can trigger acute withdrawal. Its duration is SHORTER than most opioids, so the patient can re-sedate — keep monitoring and be ready to redose.

🩸 Epistaxis5 items

Risk factors: HTN · anticoagulants · trauma · dry mucosa · steroid nasal sprays

Correct management

Correct patient position: Sitting UP and leaning FORWARD

Where should pressure be applied? Pinch the soft part of the nose — over the cartilage, not the bony bridge

How long should pressure be maintained? 10 to 15 minutes of continuous pressure, without letting go to peek

🚨 NEVER do this during a nosebleed

Do not tilt the head backward. Blood runs down the throat instead. The patient swallows it, which causes nausea and vomiting, risks aspiration, and hides how much they are actually losing.

Do not blow the nose forcefully. It dislodges the clot that just formed and starts the bleeding over again.

🗳️ Laryngeal Obstruction & Cancer of the Larynx13 items

The larynx does not stretch. Even small swelling can become life threatening fast.

🚨 RED FLAG findings

  • Stridor
  • Drooling or an inability to manage secretions
  • Severe dyspnea with retractions and accessory muscle use
  • Voice change or an inability to speak; restlessness progressing to a falling LOC

Stridor vs Wheezing

StridorWheezing
Usually indicatesUPPER airway narrowing — larynx or tracheaLOWER airway narrowing — bronchi and bronchioles
HeardLoudest over the neck, usually on inspiration; often audible without a stethoscopeOver the lung fields, usually on expiration
UrgencyEmergency — airwaySerious, but the airway is open

Cancer of the Larynx

Risk factors: smoking · alcohol · HPV · occupational exposure

Concerning manifestations: persistent hoarseness · dysphagia · weight loss · a lump in the throat

Which symptom is often ignored early? Persistent hoarseness. People write it off as a cold or overuse — but hoarseness lasting more than 2 weeks needs to be evaluated.

🎯 NCLEX-Style Questions12 items
1. Which is an EARLY sign of hypoxia?
  1. Cyanosis
  2. Bradycardia
  3. Restlessness
  4. Gray skin
Show the answer
Answer: C. Restlessness
Restlessness. The brain is the most oxygen-sensitive organ, so a change in behavior or LOC shows up before anything else. Cyanosis, bradycardia, and gray skin are all LATE — by then compensation has already failed.
2. A patient with drooling, muffled voice, and difficulty swallowing is MOST concerning for:
  1. Asthma
  2. Airway obstruction
  3. Atelectasis
  4. GERD
Show the answer
Answer: B. Airway obstruction
Airway obstruction. That triad means the patient cannot manage their own secretions and the upper airway is closing — think peritonsillar abscess or epiglottitis. Asthma causes wheezing, not drooling. GERD and atelectasis do not threaten the upper airway.
3. Which patient should the nurse see FIRST?
  1. Sore throat
  2. Hoarseness
  3. Stridor with accessory muscle use
  4. Nasal congestion
Show the answer
Answer: C. Stridor with accessory muscle use
Stridor with accessory muscle use. Stridor means the upper airway is narrowing and the accessory muscles say the patient is working hard to compensate. Airway always outranks the rest — sore throat, hoarseness, and congestion are uncomfortable but not urgent.
✅ Final Clinical Judgment Reminder4 items

Do not memorize diseases. Think through the patient.

  • What clues matter?
  • What is the priority?
  • What is happening physiologically?
  • What intervention fixes the actual problem?

Can this patient maintain an airway? Are they oxygenating effectively? Those two questions answer most of this module.

Filled from the Respiratory I guided notes handout · NUR 198 Exam 2 — Respiratory