The reversal agents you get tested on, plus 110 drugs from the guide with a documented overdose treatment.
acetaminophen → acetylcysteine
opioids → naloxone
benzodiazepines → flumazenil
Calcium is first because it stabilizes the myocardium. It does not lower the potassium.
30 pairs. The search box filters these too.
Give within 8–10 hr for best effect. Watch the rising AST/ALT, not the symptoms — the client can look fine while the liver is failing.
Shorter half-life than most opioids — it can wear off and the client re-sedates. Keep monitoring.
Can trigger seizures in chronic users or mixed TCA overdose. Use cautiously.
Add FFP or PCC when bleeding is active — vitamin K alone is too slow.
1 mg protamine per ~100 units heparin. Monitor aPTT.
Only reverses about 60% — LMWH is not fully reversible.
Direct thrombin inhibitor with its own dedicated antidote.
Factor Xa inhibitors. Expensive, not stocked everywhere.
Anorexia, nausea, yellow-green halos. Hypokalemia worsens toxicity.
Classic in OB. First sign is loss of deep tendon reflexes, then respiratory depression.
Urine turns a reddish 'vin rosé' color as iron is chelated out.
Chelation. Find the exposure source before discharge.
SLUDGE — salivation, lacrimation, urination, defecation, GI upset, emesis.
Suspect after enclosed-space smoke inhalation. Turns urine and skin red.
Pulse ox reads falsely normal — draw a carboxyhemoglobin level.
'Leucovorin rescue.' Hydrate and alkalinize the urine.
Blocks alcohol dehydrogenase so the toxic metabolite never forms.
Glucagon bypasses the blocked beta receptor. Atropine first for bradycardia.
Verapamil and diltiazem drop both rate and pressure.
Watch for a widening QRS — that is the sign to treat, not the level.
Sugammadex encapsulates rocuronium and vecuronium.
'Mad as a hatter, red as a beet, dry as a bone, hot as a hare, blind as a bat.'
Conscious and able to swallow? 15 g fast carbs, recheck in 15 min.
Malignant hyperthermia. Earliest sign is rising end-tidal CO2, not fever.
Stop the infusion, leave the catheter in to aspirate, then infiltrate the site.
Stop the infusion first. Have blood products ready.
Calcium protects the heart, it does not lower the potassium.
Also given routinely with INH to prevent peripheral neuropathy.
Tingling around the mouth, tremors, prolonged QT. See the Blood Products page.
Then antihistamines, steroids, oxygen and fluids.